"Can Medication Help Me Drive Safely? Narcolepsy treatments like modafinil (Provigil), pitolisant (Wakix), sodium oxybate (Xyrem), and stimulant drugs (Adderall, Concerta, Ritalin, and others) can help you stay awake during the day. Taking them might make it safer to drive and reduce your risk for an accident.Jul 2, 2021"