完了，美国国立卫生研究院官员最终承认纳税人资助了武汉的gain-of-function研究
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#59 Re: 完了，美国国立卫生研究院官员最终承认纳税人资助了武汉的gain-of-function研究
尼玛，最早做新冠gain-of-function的是北卡的Baric，文章2015年发表在大名丁丁的Nature Medicine杂志上 
https://www.nature.com/articles/nm.3985
(https://www.technologyreview.com/2021/0 ... -to-wuhan/)
"In 2013, the American virologist Ralph Baric approached Zhengli Shi at a meeting. Baric was a top expert in coronaviruses, with hundreds of papers to his credit, and Shi, along with her team at the Wuhan Institute of Virology, had been discovering them by the fistful in bat caves. In one sample of bat guano, Shi had detected the genome of a new virus, called SHC014, that was one of the two closest relatives to the original SARS virus, but her team had not been able to culture it in the lab.
Baric had developed a way around that problem—a technique for “reverse genetics” in coronaviruses. Not only did it allow him to bring an actual virus to life from its genetic code, but he could mix and match parts of multiple viruses. He wanted to take the “spike” gene from SHC014 and move it into a genetic copy of the SARS virus he already had in his lab. The spike molecule is what lets a coronavirus open a cell and get inside it. The resulting chimera would demonstrate whether the spike of SHC014 would attach to human cells.
If it could, then it could help him with his long-term project of developing universal drugs and vaccines against the full spectrum of SARS-like viruses that he increasingly considered sources of potential pandemics. A SARS vaccine had been developed, but it wasn’t expected to be very effective against related coronaviruses, just as flu shots rarely work against new strains. To develop a universal vaccine that will elicit an antibody response against a gamut of SARS-like viruses, you need to show the immune system a cocktail of spikes. SHC014 could be one of them.
Baric asked Shi if he could have the genetic data for SHC014. “She was gracious enough to send us those sequences almost immediately,” he says. His team introduced the virus modified with that code into mice and into a petri dish of human airway cells. Sure enough, the chimera exhibited “robust replication” in the human cells—evidence that nature was full of coronaviruses ready to leap directly to people."
起码在当时石正丽只不过是承包了抓蝙蝠、提供质粒/DNA的米帝外包任务
https://www.nature.com/articles/nm.3985
(https://www.technologyreview.com/2021/0 ... -to-wuhan/)
"In 2013, the American virologist Ralph Baric approached Zhengli Shi at a meeting. Baric was a top expert in coronaviruses, with hundreds of papers to his credit, and Shi, along with her team at the Wuhan Institute of Virology, had been discovering them by the fistful in bat caves. In one sample of bat guano, Shi had detected the genome of a new virus, called SHC014, that was one of the two closest relatives to the original SARS virus, but her team had not been able to culture it in the lab.
Baric had developed a way around that problem—a technique for “reverse genetics” in coronaviruses. Not only did it allow him to bring an actual virus to life from its genetic code, but he could mix and match parts of multiple viruses. He wanted to take the “spike” gene from SHC014 and move it into a genetic copy of the SARS virus he already had in his lab. The spike molecule is what lets a coronavirus open a cell and get inside it. The resulting chimera would demonstrate whether the spike of SHC014 would attach to human cells.
If it could, then it could help him with his long-term project of developing universal drugs and vaccines against the full spectrum of SARS-like viruses that he increasingly considered sources of potential pandemics. A SARS vaccine had been developed, but it wasn’t expected to be very effective against related coronaviruses, just as flu shots rarely work against new strains. To develop a universal vaccine that will elicit an antibody response against a gamut of SARS-like viruses, you need to show the immune system a cocktail of spikes. SHC014 could be one of them.
Baric asked Shi if he could have the genetic data for SHC014. “She was gracious enough to send us those sequences almost immediately,” he says. His team introduced the virus modified with that code into mice and into a petri dish of human airway cells. Sure enough, the chimera exhibited “robust replication” in the human cells—evidence that nature was full of coronaviruses ready to leap directly to people."
起码在当时石正丽只不过是承包了抓蝙蝠、提供质粒/DNA的米帝外包任务
上次由 windseven 在 2024年 5月 17日 23:59 修改。
#61 Re: 完了，美国国立卫生研究院官员最终承认纳税人资助了武汉的gain-of-function研究
要叫石正丽病毒也得先问问米爹“冠毒之父”巴里克同意不同意，更别说米爹NIH的白手套EcoHealth是石正丽的金主和后台老板
有“千老”敢跟老板争通讯作者、命名权的吗？
上次由 windseven 在 2024年 5月 18日 00:38 修改。
#63 Re: 完了，美国国立卫生研究院官员最终承认纳税人资助了武汉的gain-of-function研究
武汉都是美国的零时工 - 按程序操作， 其余的布吉岛？陈胜吴广 写了： 2024年 5月 17日 13:40 NIH资助了WIV是众所周知的，是公开的。
但是资助 WIV gain-of-function研究则是子虚乌有，那点钱，买试剂都不够，仅够雇一个美国人干活发工资的。
一切都是公开的，武汉也没有gain-of-function的技术。
#65 Re: 完了，美国国立卫生研究院官员最终承认纳税人资助了武汉的gain-of-function研究
完了，书这两天又中招了，好像又感染了某病毒
总设计师最大成就其实是：
俺为宝书抓翻墙的增国库收入：
把工人农民阶级偷偷顺利从国家主任忽悠成打工仔地位，偷偷改成资本主义
俺为宝书抓翻墙的增国库收入：
redot,UncleTony,chinaren,fulvshou,saibaster,mlforlife,SOD,matlab,F1450,becky,changjiang,midlander,DongshanGe,autoking,redcar,lahei
#67 Re: 完了，美国国立卫生研究院官员最终承认纳税人资助了武汉的gain-of-function研究
马勒戈壁的，叔从一开始就说要绞死福奇这个傻逼，操他妈！
叔平生最恨这种长着大嘴瞪着眼睛满嘴撒谎的傻逼！
叔平生最恨这种长着大嘴瞪着眼睛满嘴撒谎的傻逼！
