datascience和medchem的对接？？

[Tlexander]

我们的readout比较复杂，要和medchem部门沟通好，为什么要做这个assay，哪里是坑，哪些地方需要填坑，怎么解释，怎么把你们的data用回到primary assay里。前期都是各个部门一起摸石头过河，光靠Chem容易走偏。

[Tlexander]

structure activity relationship

[Tlexander]

你可以想象一下基于omics的SAR。如果没有data support，他们会把excel逼疯的

[Tlexander]

Structure-activity relationship (SAR) is a concept in chemistry and pharmacology that refers to the relationship between the chemical or structural features of a molecule and its biological activity. SAR studies are conducted to understand how changes in the structure of a molecule can affect its activity, potency, and specificity for a target receptor or enzyme. By systematically altering the structure of a molecule and testing its activity, SAR studies can help identify the key structural features responsible for its biological effects. This information can be used to design and optimize new drugs with improved efficacy and safety profiles. SAR studies are commonly used in drug discovery and development to guide the design of new drug candidates and improve their pharmacological properties.