Etrumadenant(AB928), the first dual A2a/A2b adenosine receptor antagonist to enter the clinic, is being evaluated in multiple Phase 2 and 1b studies across different indications, including prostate, colorectal, non-small cell lung, pancreatic and triple-negative breast cancers.
AB680, the first small-molecule CD73 inhibitor to enter the clinic, is in Phase 1/1b development for first-line treatment of metastatic pancreatic cancer in combination with zimberelimab and gemcitabine/nab-paclitaxel.
Domvanalimab (AB154), an anti-TIGIT monoclonal antibody and new potential immuno-oncology backbone therapy, is in a three-arm randomized Phase 2 study for first-line treatment of PD-L1-high metastatic non-small cell lung cancer (NSCLC) evaluating zimberelimab monotherapy, domvanalimab with zimberelimab and domvanalimab plus AB928 with zimberelimab.
AB308, an anti-TIGIT antibody that is FcR enabled, is advancing into clinical development to investigate additional indications, with a focus on hematological malignancies. Zimberelimab (AB122), Arcus’s anti-PD-1 monoclonal antibody, was in-licensed to enable the development of Arcus’s combination regimens and is being evaluated in various combinations across the portfolio.
Arcus Biosciences @ Bay Area SF
生物制药相关,包括biotech和pharma,股票分析,工作内推,简历评估,职业规划,研发交流,FDA资讯等
版主: Tlexander
-
- 论坛点评
- 帖子: 2957
- 注册时间: 7月 22, 2022, 5:34 pm
前往
- 新闻中心
- ↳ 军事天地(Military)
- ↳ 肚皮舞运动(Joke)
- ↳ 精华区
- ↳ 美国新闻(USANews)
- ↳ 史海钩沉(History)
- ↳ 台海风云(TaiwanStrait)
- ↳ 精华区
- ↳ 中国新闻(ChinaNews)
- ↳ 捕风捉影(Plausible)
- ↳ 美国时政(US Current Affairs)
- ↳ 精华区
- 海外生活
- ↳ 股海弄潮(Stock)
- ↳ 股海弄潮精华区
- ↳ 家居生活(Living)
- ↳ 精华区
- ↳ 车轮上的传奇(Automobile)
- ↳ 二手市场(FleaMarket)
- ↳ 书歌影视美食游
- ↳ 精华区
- ↳ 电脑手机(IT)
- ↳ 精华区
- ↳ 子女教育
- ↳ 精华区
- ↳ 手机计划(Cellular Plan)
- ↳ 信仰天地(Belief)
- ↳ 投资理财退税(Money)
- ↳ 海外鹊桥(Chinese Dating)
- ↳ 医疗与健康
- 学术学科
- ↳ STEM
- ↳ 葵花宝典(Programming)
- ↳ 生物医学(Biomedical)
- ↳ 统计与数据科学(Statistics & DataScience)
- ↳ 前沿科技(Frontier)
- ↳ 金融量化(Invest)
- 职场生涯
- ↳ 生物制药(Pharmaceutical)
- ↳ 绿卡移民(Immigration)
- ↳ 职场讨论
- 情感杂想
- ↳ 梦里花落知多少(Dreamer)
- ↳ 人到中年(Midlife)
- ↳ 性意识(Sex)
- 体育健身
- ↳ 滚吧,足球!(Soccer )
- ↳ 体育博彩
- ↳ 奥运和综合体育
- ↳ 网球(Tennis)
- 休闲娱乐
- ↳ 摄影器材(Photo gears)
- ↳ 网络文学
- ↳ 花鸟鱼虫
- ↳ 枪械射击(Guns & Gear)
- ↳ 新未名博客(Blog)
- 华人世界
- ↳ 加州华人
- ↳ 广告与招聘
- 站务管理
- ↳ 申请新版块或版主
- ↳ 意见与建议
- ↳ 版主专区
- ↳ 账号管理
- ↳ 论坛使用交流
- ↳ 功能测试