Paxlovid does not work

[whoami]

这个David McCune， 在推特上8231个followers。这得多傻逼才信他的话。哦，忘了，你就是傻逼。

keyword： faith based medicine 谁信谁傻逼

“I think Pfizer has a plaque ready for the first provider to give a healthy, triple vaxxed, prior infected kid a course of paxlovid. It would be hitting for the faith-based medicine cycle.” - David McCune, MD, MPH

[CutPaste]

插吸族掌控的西医疗业的突破性空前成就：

1. 发明了金钱永动机，比核聚变更厉害。

超暴利的Perpetual Money Machine。

2. 给全球狗蝇颁发了近千万个达尔文奖。

无数崇洋媚外老中还在排长队等获殊荣。








.

[whoami]

你个傻逼，去数数中国有多少西医院和多少中医院吧。你是傻逼，别人不是。

在去看看西医引入之后，新生儿的存活率吧。没有西医，你他妈说不定早夭折了。lol

插吸族掌控的西医疗业的突破性空前成就：

1. 发明了金钱永动机，比核聚变更厉害。

超暴利的Perpetual Money Machine。

2. 给全球狗蝇颁发了近千万个达尔文奖。

无数崇洋媚外老中还在排长队等获殊荣。








.

[CutPaste]

你个傻逼，去数数中国有多少西医院和多少中医院吧。你是傻逼，别人不是。

在去看看西医引入之后，新生儿的存活率吧。没有西医，你他妈说不定早夭折了。lol

我几十年没看西医或中医。

几十年没打任何疾病疫苗。

几十年没吃任何西药中药。

也没去参与医疗业的礼仪。

礼仪包括各种辐射性体检。

因我有突破性的知识技术。



.

[张雅婷粉58Red2]

Pfizer re-packaged HIV/AIDS medication Ritonavir (with nirmatrelvir) as 'Paxlovid', their new Covid treatment.

[Scraper]

Pfizer re-packaged HIV/AIDS medication Ritonavir (with nirmatrelvir) as 'Paxlovid', their new Covid treatment.

看名字象核苷类药，慎用。

[张雅婷粉58Red2]

https://en.wikipedia.org/wiki/Nirmatrelvir

工作原理：
In the co-packaged medication nirmatrelvir/ritonavir, ritonavir serves to slow the metabolism of nirmatrelvir via cytochrome enzyme inhibition, thereby increasing the circulating concentration of the main drug.[22] This effect is also used in HIV therapy, where ritonavir is used in combination with another protease inhibitor to similarly enhance their pharmacokinetics.[23]

研究开发
The research that led to nirmatrelvir began on 16 March 2020, when Pfizer formally launched a project at its Cambridge, Massachusetts site to develop antiviral drugs for treating COVID-19.[15] On 22 July 2020, Pfizer chemists were able to synthesize nirmatrelvir for the first time, although the importance of that moment was not clear then because it was just one of 20 candidates synthesized that week.[15] On 1 September 2020, Pfizer completed a pharmacokinetic study in rats which suggested that nirmatrelvir could be administered orally.[15] The actual synthesis of the drug for laboratory research and for clinical trials was carried out at Pfizer's Groton, Connecticut site.[27]

In February 2021, Pfizer launched the company's first phase I trial of PF-07321332 (nirmatrelvir)[28] at its clinical research unit in New Haven, Connecticut.[27] According to Chemical & Engineering News, the drug went "from an idea to the first clinical test in a person in 12 months—a breathtaking pace at which to deliver a bespoke drug candidate."[15]

[张雅婷粉58Red2]

https://off-guardian.org/2022/04/01/rus ... eat-covid/
经销商：

[张雅婷粉58Red2]

Just give us Ivermectin and be done with it. lol

Not sure how good this Ivermectin alternative is. But here it is:

[张雅婷粉58Red2]

fda approval letter:

https://www.fda.gov/media/155049/download

[Scraper]

https://sites.dartmouth.edu/dujs/2021/1 ... -paxlovid/

这网页介绍深入浅出，不错。

[whoami]

https://cen.acs.org/articles/100/i3/How ... viral.html

How Pfizer scientists transformed an old drug lead into a COVID-19 antiviral

What’s more, Pfizer already had a lead in hand. In 2003, researchers at the company developed an antiviral, known as PF-00835231, that could block the main protease of a coronavirus that emerged in 2002 and causes severe acute respiratory syndrome (SARS). But by the time they were ready to test it in patients, the SARS outbreak had been contained.

这个program从2003年就有了，而且有了lead。现在是加以改进。

https://en.wikipedia.org/wiki/Nirmatrelvir

工作原理：
In the co-packaged medication nirmatrelvir/ritonavir, ritonavir serves to slow the metabolism of nirmatrelvir via cytochrome enzyme inhibition, thereby increasing the circulating concentration of the main drug.[22] This effect is also used in HIV therapy, where ritonavir is used in combination with another protease inhibitor to similarly enhance their pharmacokinetics.[23]

研究开发
The research that led to nirmatrelvir began on 16 March 2020, when Pfizer formally launched a project at its Cambridge, Massachusetts site to develop antiviral drugs for treating COVID-19.[15] On 22 July 2020, Pfizer chemists were able to synthesize nirmatrelvir for the first time, although the importance of that moment was not clear then because it was just one of 20 candidates synthesized that week.[15] On 1 September 2020, Pfizer completed a pharmacokinetic study in rats which suggested that nirmatrelvir could be administered orally.[15] The actual synthesis of the drug for laboratory research and for clinical trials was carried out at Pfizer's Groton, Connecticut site.[27]

In February 2021, Pfizer launched the company's first phase I trial of PF-07321332 (nirmatrelvir)[28] at its clinical research unit in New Haven, Connecticut.[27] According to Chemical & Engineering News, the drug went "from an idea to the first clinical test in a person in 12 months—a breathtaking pace at which to deliver a bespoke drug candidate."[15]

[TSG]

一群粉毛无知的令人发指，Paxlovid里有两种成分，一种是新冠病毒逆转录酶的特异性抑制剂，一种是HIV的蛋白酶抑制剂因为这个蛋白酶抑制剂同时抑制体内代谢药物的CYP3A, 可以让新冠病毒逆转录酶的特异性抑制剂在体内药代动力延长。说了也白说，翻墙发帖的好好吃退烧药反正也不是给你们用的lol

[whoami]

赞一个

一群粉毛无知的令人发指，Paxlovid里有两种成分，一种是新冠病毒逆转录酶的特异性抑制剂，一种是HIV的蛋白酶抑制剂因为这个蛋白酶抑制剂同时抑制体内代谢药物的CYP3A, 可以让新冠病毒逆转录酶的特异性抑制剂在体内药代动力延长。说了也白说，翻墙发帖的好好吃退烧药反正也不是给你们用的lol

[张雅婷粉58Red2]

Enough said.

[张雅婷粉58Red2]

The FDA and CDC are "captured" federal agencies and operate for the benefit of big pharma and not the people, for more on how they operate see Robert F.Kennedy Jr.'s excellent book"The real Anthony Fauci".

[张雅婷粉58Red2]

[_notalandlord]

本来就是＂防重症＂，不是练成金刚不坏之躯！那样就不是这个价了